Antibody Job FMV04 「№34026」 Detail

Inputs

Status
Job ID34026
Job NameFMV04
Visibility PUBLIC
Protocolantibody
CPU hours used871.096944444
user
StatusDeleted
Description
Model H3 loop
Multiple-Template GraftingFalse
Submitted time2017-08-05 06:12
Start time2017-08-05 06:12
End time2017-08-05 10:55
DaemonGrayLab.Rosetta



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[Input json]
[Output json]


Please cite the following article when referring to results from our ROSIE server:

  1. Sivasubramanian A, Sircar A, Chaudhury S, Gray JJ., "Toward high-resolution homology modeling of antibody Fv regions and application to antibody-antigen docking". Proteins. 2009 Feb 1;74(2):497-514. doi: 10.1002/prot.22309. Link

  2. Marze, N. A. & Gray, J. J. "Improved Prediction of Antibody VL-VH Orientation," Protein Eng. Des. Sel. 29(10) (2016) Online.

  3. Weitzner BD & Gray JJ "Accurate structure prediction of CDR H3 loops enabled by a novel structure-based C-terminal constraint," J. Immunology 198(1) (2017) Online.

  4. Weitzner BD, Jeliazkov JR, Lyskov S, Marze N, Kuroda D, Frick R, Adolf-Bryfogle A, Biswas N & Gray JJ "Modeling and docking antibody structures with Rosetta," Nature Protocols 12(2) (2017) Online.

  5. Lyskov S, Chou FC, Conchúir SÓ, Der BS, Drew K, Kuroda D, Xu J, Weitzner BD, Renfrew PD, Sripakdeevong P, Borgo B, Havranek JJ, Kuhlman B, Kortemme T, Bonneau R, Gray JJ, Das R., "Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)". PLoS One. 2013 May 22;8(5):e63906. doi: 10.1371/journal.pone.0063906. Print 2013. Link

Additional references of interest:

  • A. Sircar, E. Kim, & J. J. Gray, "RosettaAntibody: Antibody Variable Region Homology Modeling Server," Nucleic Acids Research 37 (Web Server Issue), W474-W479 (2009). Link