Fixed Backbone Redesign Server Documentation

Inputs

Tips

The server will not accept PDBs larger than 400 residues total.
The PDB file format description can be found here. Currently the PDB file can only contain standard protein residues. You have to remove heteroatoms (such as ligands) and convert selenomethionine residues to methionine etc. Some PDBs may also have multiple conformations for each residue.

Interpreting Results

The server returns the 10 best-scoring structures from the run in rank order by energy. Click on the [Model-N] link to download the PDB file (see below).

Please cite the following article when referring to results from our ROSIE server:

Lyskov S, Chou FC, Conchúir SÓ, Der BS, Drew K, Kuroda D, Xu J, Weitzner BD, Renfrew PD, Sripakdeevong P, Borgo B, Havranek JJ, Kuhlman B, Kortemme T, Bonneau R, Gray JJ, Das R., "Serverification of Molecular Modeling Applications: The Rosetta Online Server That Includes Everyone (ROSIE)". PLoS One. 2013 May 22;8(5):e63906. doi: 10.1371/journal.pone.0063906. Print 2013. Link

We welcome scientific and technical comments on our server. For support please contact us at Rosetta Forums with any comments, questions or concerns.

Rosie implementation of FixBB developed by Nathan Rice